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EAI045

EAI045 ia a potent and selective EGFR inhbitor. EAI045 targets selected drug-resistant EGFR mutants but spares the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays.

Product Specifications

CAS Number

1942114-09-1

Product Name Alternative

EAI045 | EAI-045 | EAI 045

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 28 mg/mL; 73.03 mM

Smiles

C1ccc2c (c1) CN (C2=O) C (C (=O) Nc1sccn1) c1cc (ccc1O) F

Molecular Formula

C19H14FN3O3S

Molecular Weight

383.4

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2- (5-fluoro-2-hydroxyphenyl) -2- (3-oxo-1H-isoindol-2-yl) -N- (1,3-thiazol-2-yl) acetamide

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