SEA-0400
SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. SEA0400 reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. SEA0400 attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury.
Product Specifications
CAS Number
223104-29-8
Product Name Alternative
SEA0400 | SEA-0400 | SEA 0400
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 32 mg/mL; 86.17 mM
Smiles
CCOc1cc (c (cc1) Oc1ccc (cc1) OCc1c (ccc (c1) F) F) N
Molecular Formula
C21H19F2NO3
Molecular Weight
371.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-[4-[ (2,5-difluorophenyl) methoxy]phenoxy]-5-ethoxyaniline
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