SB415286
SB-415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM. Pharmacological GSK-3 inhibitors are potential drugs for the treatment of neurodegenerative diseases, cancer and diabetes.
Product Specifications
CAS Number
264218-23-7
Product Name Alternative
SB-415286 | SB 415286 | SB415286
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 83.3 mg/mL; 231.57 mM
Smiles
OC1=C (Cl) C=C (NC2=C (C (=O) NC2=O) C2=C (C=CC=C2) [N+] ([O-]) =O) C=C1
Molecular Formula
C16H10ClN3O5
Molecular Weight
359.72
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-[ (3-chloro-4-hydroxyphenyl) amino]-4- (2-nitrophenyl) -1H-pyrrole-2,5-dione
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