BQCA
BQCA is a potent muscarinic M1 receptor positive allosteric modulator with selectivity for M1 over M2-M5. Stimulation of the cortical muscarinic M1 receptor (CHRM1) is proposed as a treatment for schizophrenia, a hypothesis testable using CHRM1 allosteric modulators. BQCA binds allosterically to M1 to enhance the binding and efficacy of ACh at the receptor. M1 activation is a proposed mechanism for increasing information processing in disease states, such as Alzheimer′s.
Product Specifications
CAS Number
338747-41-4
Product Name Alternative
BQCA, CAS#338747-41-4
Purity
>98% (HPLC)
Solubility
DMSO : 5.45 mg/mL. 17.62 mM
Smiles
COC1=CC=C (C=C1) CN2C=C (C (=O) C3=CC=CC=C32) C (=O) O
Molecular Formula
C18H15NO4
Molecular Weight
309.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (4-methoxybenzyl) -4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Available Sizes
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