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LM22B-10

LM22B-10 is a TrkB and TrkC agonist. LM22B-10 exhibits neurotrophic activity (EC50 = 200-300 nM) . LM22B-10 improves survival and increases neurite outgrowth in hippocampal cells in vitro. LM22B-10 increased cell survival and strongly accelerated neurite outgrowth, superseding the effects of brain-derived neurotrophic factor (BDNF), NT-3 or the two combined.

Product Specifications

CAS Number

342777-54-2

Product Name Alternative

LM22B-10 | LM22B 10 | LM22B10

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 150 mg/mL; 309.27 mM

Smiles

Clc1ccc (cc1) C (c2ccc (cc2) N (CCO) CCO) c3ccc (cc3) N (CCO) CCO

Molecular Formula

C27H33ClN2O4

Molecular Weight

485.01

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2,2',2',2'''-[[ (4-Chlorophenyl) methylene]bis (4,1-phenylenenitrilo) ]tetrakisethanol

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