CP-724714
CP-724714 is An orally bioavailable quinazoline with potential antineoplastic activity. CP-724,714 selectively binds to the intracellular domain of HER2, reversibly inhibiting its tyrosine kinase activity and resulting in suppression of tumor cell growth. HER2, a member of the epidermal growth factor receptor (EGFR) family, is overexpressed in many adenocarcinomas, particularly breast cancers.
Product Specifications
CAS Number
383432-38-0
Product Name Alternative
CP724714 | CP 724714 | CP-724714
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 50 mg/mL; 106.49 mM
Smiles
Cc1ncc (cc1) Oc1c (cc (cc1) Nc1ncnc2c1cc (cc2) /C=C/CNC (=O) COC) C
Molecular Formula
C27H27N5O3
Molecular Weight
469.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(E) -2-methoxy-N- (3- (4- (3-methyl-4- (6-methylpyridin-3-yloxy) phenylamino) quinazolin-6-yl) allyl) acetamide.
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