ISO-1
ISO-1, also known as MIF Antagonist and ISO-1 and Macrophage Migration Inhibitory Factor, is a MIF inhibitor. ISO-1 has CAS#478336-92-4. MDK-6924 Protects Photoreceptors and Reduces Gliosis in Experimental Retinal Detachment. Systemic administration of the MIF inhibitor ISO-1 significantly blocked photoreceptor apoptosis, outer nuclear layer (ONL) thinning, and retinal gliosis. ISO-1 and MIF knockout (MIFKO) had greater accumulation of Müller glia pERK expression in the detached retina, suggesting that Müller survival pathways might underlie the neuroprotective response.
Product Specifications
CAS Number
478336-92-4
Product Name Alternative
ISO-1 | ISO 1 | ISO1 | MIF Antagonist
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 36 mg/mL; 153.04 mM
Smiles
COC (=O) CC1CC (=NO1) c1ccc (O) cc1
Molecular Formula
C12H13NO4
Molecular Weight
235.2
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4,5-dihydro-3- (4-hydroxyphenyl) -5-isoxazoleacetic acid, methyl ester
Available Sizes
Frequently Asked Questions
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