GW 441756
GW-441756 is a potent inhibitor of TrkA (IC50 = 2 nM) . Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma.
Product Specifications
CAS Number
504433-23-2
Product Name Alternative
GW-441756 | GW 441756 | GW441756
Purity
>98% (HPLC)
Solubility
DMSO : 17.5 mg/mL. 63.57 mM; H2O : < 0.1 mg/mL
Smiles
Cn1cc (c2ccccc12) C=C1c2c (cccn2) NC1=O
Molecular Formula
C17H13N3O
Molecular Weight
275.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,3-dihydro-3-[ (1-methyl-1H-indol-3-yl) methylene]-2H-pyrrolo[3,2-b]pyridin-2-one
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