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GW 441756

GW-441756 is a potent inhibitor of TrkA (IC50 = 2 nM) . Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma.

Product Specifications

CAS Number

504433-23-2

Product Name Alternative

GW-441756 | GW 441756 | GW441756

Purity

>98% (HPLC)

Solubility

DMSO : 17.5 mg/mL. 63.57 mM; H2O : < 0.1 mg/mL

Smiles

Cn1cc (c2ccccc12) C=C1c2c (cccn2) NC1=O

Molecular Formula

C17H13N3O

Molecular Weight

275.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1,3-dihydro-3-[ (1-methyl-1H-indol-3-yl) methylene]-2H-pyrrolo[3,2-b]pyridin-2-one

Available Sizes

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