3-MATIDA
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a) . Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM) . 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
Product Specifications
CAS Number
518357-51-2
Product Name Alternative
3-MATIDA
Purity
>98% (HPLC)
Smiles
Cc1c (sc (c1) C (=O) O) C (C (=O) O) N
Molecular Formula
C8H9NO4S
Molecular Weight
215.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Methyl-aminothiophene dicarboxylic acid; 5- (Amino (carboxy) methyl) -4-methylthiophene-2-carboxylic acid
Available Sizes
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