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3-MATIDA

3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a) . Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM) . 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.

Product Specifications

CAS Number

518357-51-2

Product Name Alternative

3-MATIDA

Purity

>98% (HPLC)

Smiles

Cc1c (sc (c1) C (=O) O) C (C (=O) O) N

Molecular Formula

C8H9NO4S

Molecular Weight

215.22

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

3-Methyl-aminothiophene dicarboxylic acid; 5- (Amino (carboxy) methyl) -4-methylthiophene-2-carboxylic acid

Available Sizes

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