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BIO-acetoxime

BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. Also, BIO-Acetoxime induces Wnt signaling and inhibits CD8+ T cell effector differentiation. BIO-acetoxime is a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus. BIO-Acetoxime protects cells from varicella infection. BIO-acetoxime may suppress viral gene expression and protect oral epithelial cells from HSV-1 infection.

Product Specifications

CAS Number

667463-85-6

Product Name Alternative

BIO-acetoxime | 6-Bromoindirubin-3′-acetoxime, BIA

Purity

>98% (HPLC)

Solubility

DMSO : 20.83 mg/mL. 52.31 mM; H2O : < 0.1 mg/mL

Smiles

CC (=O) O\N=C1C2=CC=CC=C2NC/1=C1\C (=O) NC2=C1C=CC (Br) =C2

Molecular Formula

C18H12BrN3O3

Molecular Weight

398.21

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(2Z,3E) -3- (acetoxyimino) -6'-bromo-[2,3'-biindolinylidene]-2'-one

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