MonoMethyl auristatin F
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. MMAF is actually desmethyl-auristatin F; that is, the N-terminal amino group has only one methyl substituent instead of two as in auristatin F itself.
Product Specifications
CAS Number
745017-94-1
Product Name Alternative
Monomethyl auristatin F | MMAF
Purity
>98% (HPLC)
Smiles
CC[C@H] (C) [C@@H] ([C@@H] (CC (=O) N1CCC[C@H]1[C@@H] ([C@@H] (C) C (=O) N[C@@H] (Cc1ccccc1) C (=O) O) OC) OC) N (C) C (=O) [C@H] (C (C) C) NC (=O) [C@H] (C (C) C) NC
Molecular Formula
C39H65N5O8
Molecular Weight
731.98
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
((2R,3R) -3- ((2S) -1- ((3R,5S) -4- ((S) -N,3-dimethyl-2- ((S) -3-methyl-2- (methylamino) butanamido) butanamido) -3-methoxy-5-methylheptanoyl) pyrrolidin-2-yl) -3-methoxy-2-methylpropanoyl) -L-phenylalanine
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC550017-100 1x 100 µL
Ep-CAM / CD326 (VU-1D9), CF555 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400226-100 1x 100 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402642-100 1x 100 µL
Prolactin (Pituitary Tumor Marker) (PRL/2642), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040052-100 1x 100 µL
HCG-intact (HCGab/52), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472230-100 1x 100 µL
FOXA1 / HNF3A (FOXA1/2230R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681224-500 1x 500 µL
HCG-beta (HCGb/54+ HCGb/459), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details