Tedizolid Phosphate
Tedizolid is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. (In Vitro) :Tedizolid phosphate (TR-701FA; 0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP. (In Vivo) :For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate (TR-701FA) at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema.
Product Specifications
CAS Number
856867-55-5
Product Name Alternative
TR-701FA
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 36 mg/mL. 79.94 mM. H2O : 0.1 mg/mL0.22 mM
Smiles
CN1N=NC (=N1) C1=NC=C (C=C1) C1=CC=C (C=C1F) N1C[C@H] (COP (O) (O) =O) OC1=O
Molecular Formula
C17H16FN6O6P
Molecular Weight
450.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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