FTIDC
FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.
Product Specifications
CAS Number
873551-53-2
Product Name Alternative
FTIDC
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : ≥ 100 mg/mL (279.01 mM)
Smiles
C1CC (=CCN1C (=O) N (C (C) C) C) c1nnn (c1C) c1c (nccc1) F
Molecular Formula
C18H23FN6O
Molecular Weight
358.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-[1- (2-Fluoropyridin-3-yl) -5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1 (2H) -carboxamide
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