ZK 756326
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse) . Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors) . Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
Product Specifications
CAS Number
874911-96-3
Purity
>98% (HPLC)
Smiles
C1CN (CCN1CCOCCO) CC2=CC (=CC=C2) OC3=CC=CC=C3.Cl.Cl
Molecular Formula
C21H28N2O3·2HCl
Molecular Weight
429.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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