MN-64
MN-64 is a potent and selective inhibitor of Tankyrase 1 and 2 (IC50 = 6 and 72 nM, respectively) . MN-64 blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system. Tankyrases are ADP-ribosyltransferases that play key roles in various cellular pathways, including the regulation of cell proliferation, and thus, they are promising drug targets for the treatment of cancer.
Product Specifications
CAS Number
92831-11-3
Product Name Alternative
MN-64 | MN 64 | MN64
Purity
>98% (HPLC)
Solubility
DMSO : 100 mg/mL. 378.33 mM
Smiles
CC (C) c1ccc (cc1) c1cc (=O) c2ccccc2o1
Molecular Formula
C18H16O2
Molecular Weight
264.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-[4- (1-Methylethyl) phenyl]-4H-1-benzopyran-4-one
Available Sizes
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