AR-42
AR-42, also known as (S) -HDAC-42; AR-42; NSC-736012; OSU-42; OSU-HDAC-42; OSUHDAC-42, is a broad-spectrum deacetylase inhibitor of both histone and non-histone proteins, which has demonstrated greater potency and activity in solid tumors and hematological malignancies when compared in preclinical studies to vorinostat (also known as "SAHA" or Zolinza), the first of two marketed compound in the class. AR-42 may possess additional histone-independent mechanisms, which may contribute to its superior profile in vitro and in vivo.
Product Specifications
CAS Number
935881-37-1
Product Name Alternative
AR42 | AR 42 | (S) -HDAC-42 | AR-42 | NSC-736012 | OSU-42
Purity
>98% (HPLC)
Solubility
In Vitro: Ethanol : 50 mg/mL (160.07 mM)
Smiles
CC (C) [C@H] (C (=O) Nc1ccc (cc1) C (=O) NO) c1ccccc1
Molecular Formula
C18H20N2O3
Molecular Weight
312.36
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(S) -N-hydroxy-4- (3-methyl-2-phenylbutanamido) benzamide
Available Sizes
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