JK-P3
JK-P3 is novel inhibitor of VEGFR-2. JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50 = 7.8 μM) . JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
Product Specifications
CAS Number
942655-44-9
Product Name Alternative
3,4-Dimethoxy-N- (5-phenyl-1H-pyrazol-3-yl) -benzamide
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (154.63 mM)
Smiles
COc1c (cc (cc1) C (=O) Nc1n[nH]c (c1) c1ccccc1) OC
Molecular Formula
C18H17N3O3
Molecular Weight
323.35
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3,4-Dimethoxy-N- (5-phenyl-1H-pyrazol-3-yl) -benzamide
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