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DY-131

DY131, also known as GSK-9089, is a novel selective agonist at estrogen-related receptors ERRβ and ERRγ. DY131 could potentiate the ERRgamma-induced growth inhibition in LNCaP-ERRgamma and DU145-ERRgamma cells in a dose-dependent manner. ERRgamma may perform an antiproliferative or tumor-suppressing function in prostate cancer cells. ERRgamma could be a novel therapeutic target for prostate cancer treatment.

Product Specifications

CAS Number

95167-41-2

Product Name Alternative

DY131 | DY-131 | DY 131 | GSK-9089

Purity

>98% (HPLC)

Solubility

DMSO : 50 mg/mL. 160.58 mM

Smiles

C (=O) (c1ccc (cc1) O) N/N=C/c1ccc (cc1) N (CC) CC

Molecular Formula

C18H21N3O2

Molecular Weight

311.38

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(E) -N'- (4- (diethylamino) benzylidene) -4-hydroxybenzohydrazide

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