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NIH-12848

NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.

Product Specifications

CAS Number

959551-10-1

Product Name Alternative

NIH-12848 | NCGC00012848-02.

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 28 mg/mL; 72.65 mM

Smiles

FC (F) (F) c1ccccc1c1nc2ccccc2c (NCc2cccs2) n1

Molecular Formula

C20H14F3N3S

Molecular Weight

385.41

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (thiophen-2-ylmethyl) -2- (2- (trifluoromethyl) phenyl) quinazolin-4-amine

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