NIH-12848
NIH-12848 is a putative phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) inhibitor. NIH-12848 inhibited PI5P4Kγ with an IC50 of approximately 1 μM but did not inhibit the α and β PI5P4K isoforms at concentrations up to 100 μM. NIH-12848 is a potentially powerful tool for exploring the cell physiology of PI5P4Ks.
Product Specifications
CAS Number
959551-10-1
Product Name Alternative
NIH-12848 | NCGC00012848-02.
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 28 mg/mL; 72.65 mM
Smiles
FC (F) (F) c1ccccc1c1nc2ccccc2c (NCc2cccs2) n1
Molecular Formula
C20H14F3N3S
Molecular Weight
385.41
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (thiophen-2-ylmethyl) -2- (2- (trifluoromethyl) phenyl) quinazolin-4-amine
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