Splitomicin
Splitomicin is a cell-permeable lactone derived from naphthol and known to be a potent selective inhibitor of Sir2 (silent information regulator 2) and HDAC. Splitomicin inhibits the NAD+-dependent deacetylase activity of Sir2 in vitro. It increases the levels of cyclic AMP by inhibiting the activity of cyclic AMP phosphodiesterase, interferes with mobilization of intracellular Ca+2 and ATP release.
Product Specifications
CAS Number
5690-03-9
Product Name Alternative
Splitomicin
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (504.49 mM)
Smiles
O=C1CCc2c3ccccc3ccc2O1
Molecular Formula
C13H10O2
Molecular Weight
198.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-benzo[f]chromen-3 (2H) -one
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-52798R-Biotin 100 µL
MMP13 Recombinant Antibody, Biotin Conjugated
Sign In for Pricing
View Details 
LS064753-20ug 20 µg
CCDC136 (NM_022742) Human Over-expression Lysate
Sign In for Pricing
View Details 
MBS653105-01 100 g
Drop-out Base (w/o aa) With Glucose and Agar (Powder)
Sign In for Pricing
View Details MBS653105-02 500 g
Drop-out Base (w/o aa) With Glucose and Agar (Powder)
Sign In for Pricing
View Details MBS653105-03 5x 500 g
Drop-out Base (w/o aa) With Glucose and Agar (Powder)
Sign In for Pricing
View Details