GNF-5837
GNF-5837 is a potent, selective, and orally bioavailable pan-TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. The properties of GNF-5837 make it a good tool for the elucidation of TRK biology in cancer and other nononcology indications.
Product Specifications
CAS Number
1033769-28-6
Product Name Alternative
GNF5837 | GNF-5837 | GNF 5837
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 32 mg/mL; 59.76 mM
Smiles
Cc1c (cc (cc1) NC (=O) Nc1c (ccc (c1) C (F) (F) F) F) Nc1cc2c (cc1) /C (=C/c1ccc[nH]1) /C (=O) N2
Molecular Formula
C28H21F4N5O2
Molecular Weight
535.49
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(Z) -1- (3- ((3- ((1H-pyrrol-2-yl) methylene) -2-oxoindolin-6-yl) amino) -4-methylphenyl) -3- (2-fluoro-5- (trifluoromethyl) phenyl) urea
Available Sizes
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