Caffeic Acid Phenethyl Ester
Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF) -1alpha and subsequent induction of heme oxygenase-1 (HO-1) .
Product Specifications
CAS Number
104594-70-9
Product Name Alternative
CAPE | Caffeic Acid Phenethyl Ester | β-Phenylethyl Caffeate
Purity
>98% (HPLC)
Solubility
DMSO : 150 mg/mL. 527.59 mM
Smiles
C1ccc (cc1) CCOC (=O) /C=C/c1ccc (c (c1) O) O
Molecular Formula
C17H16O4
Molecular Weight
284.31
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Phenylethyl (E) -3- (3,4-dihydroxyphenyl) prop-2-enoate
Available Sizes
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