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Caffeic Acid Phenethyl Ester

Caffeic Acid Phenethyl Ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF) -1alpha and subsequent induction of heme oxygenase-1 (HO-1) .

Product Specifications

CAS Number

104594-70-9

Product Name Alternative

CAPE | Caffeic Acid Phenethyl Ester | β-Phenylethyl Caffeate

Purity

>98% (HPLC)

Solubility

DMSO : 150 mg/mL. 527.59 mM

Smiles

C1ccc (cc1) CCOC (=O) /C=C/c1ccc (c (c1) O) O

Molecular Formula

C17H16O4

Molecular Weight

284.31

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-Phenylethyl (E) -3- (3,4-dihydroxyphenyl) prop-2-enoate

Available Sizes

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