Ascomycin
Ascomycin, also known as KF-520, FR900520, L 683590, produced by the fermentation of S. hygroscopicus subsp. ascomyceticus, is an ethyl analog of tacrolimus (FK-506) with potent immunosuppressant properties.
Product Specifications
CAS Number
104987-12-4
Product Name Alternative
FK-520 | FR900520 | L-683590 | Changchuanmycin
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 39 mg/mL; 49.24 mM
Smiles
O1[C@@]2 (O) C (=O) C (=O) N3[C@H] (C (=O) O[C@@H] ([C@@H] ([C@@H] (O) CC (=O) [C@@H] (/C=C (/C[C@@H] (C[C@H] (OC) [C@@H]1[C@@H] (OC) C[C@H]2C) C) \C) CC) C) /C (=C/[C@H]1C[C@@H] (OC) [C@H] (O) CC1) /C) CCCC3
Molecular Formula
C43H69NO12
Molecular Weight
792.01
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS) -8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[ (1E) -2-[ (1R,3R,4R) -4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21 (4H,23H) -tetrone
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