Nomilin
Nomilin is an inducer of phase II detoxifying enzymes, showing anti-proliferative active on cultured human breast cancer cells. (In Vitro) :Nomilin treatment significantly mitigated cell death and decreased lactate dehydrogenase (LDH) release and ROS production in SH-SY5Y cells induced by oxygen-glucose deprivation (OGD), which was almost abolished by Nrf2 knockdown. (In Vivo) :Nomilin attenuated blood-brain barrier (BBB) disruption in MCAO rats, which might be associated with alleviating the loss of tight junction proteins, including ZO-1 and occludin-5.
Product Specifications
CAS Number
1063-77-0
Product Name Alternative
Nomilin
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (194.34 mM)
Smiles
CC (=O) OC5CC (=O) O[C@@] (C) (C) [C@@H]6CC (=O) [C@]3 (C) [C@H] (CC[C@@]2 (C) [C@@H] (OC (=O) [C@H]1O[C@]123) c4ccoc4) [C@@]56C
Molecular Formula
C28H34O9
Molecular Weight
514.57
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (Acetyloxy) -1,2-dihydroobacunoic acid e-lactone
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