Loxiglumide
Loxiglumide is a potent, orally active, and selective CCK-A receptor antagonist which stimulates calorie intake and hunger feelings in humans. Loxiglumide inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. Intravenous administration of loxiglumide antagonized the CCK-induced reduction of gastric emptying in rats, acceleration of intestinal transport in mice, increase in ileal motility in rabbits, gallbladder contraction in guinea pigs and acceleration of gallbladder emptying in mice.
Product Specifications
CAS Number
107097-80-3
Product Name Alternative
CR-1505 | Loxiglumide, brand name: Loxizin.
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 150 mg/mL; 325.11 mM
Smiles
CCCCCN (CCCOC) C (=O) C (CCC (=O) O) NC (=O) c1cc (c (cc1) Cl) Cl
Molecular Formula
C21H30Cl2N2O5
Molecular Weight
461.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (3,4-dichlorobenzamido) -5- ((3-methoxypropyl) (pentyl) amino) -5-oxopentanoic acid
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