Polaprezinc
Polaprezinc is an orally bioavailable chelate composed of zinc and L-carnosine, with potential gastroprotective, anti-oxidant, anti-ulcer and anti-inflammatory activities. Upon administration, polaprezinc increases the expression of various anti-oxidant enzymes, such as superoxide dismutase 1 (SOD-1), SOD-2, heme oxygenase-1 (HO-1), glutathione S-transferase (GST), glutathione peroxidase (GSH-px), peroxidredoxin-1 (PRDX1; PRXI) and PRXD5 (PRXV) in the gastric mucosa, which protect cells against reactive oxygen species (ROS) .
Product Specifications
CAS Number
107667-60-7
Product Name Alternative
Polaprezinc | Z 103
Purity
>98% (HPLC)
Solubility
H2O : 3.37 mg/mL 11.68 mM; DMSO : < 1 mg/mL
Smiles
NCCC (=O) N1[Zn]OC (=O) [C@@H]1Cc1cnc[nH]1
Molecular Formula
C9H12N4O3Zn
Molecular Weight
289.63
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Catena-Poly (zinc-mu- (beta-alanyl-L-histidinato (2 (-) ) -N, N (sup N), O:N (sup tau) ) )
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