JZL184
JZL184 is highly selective, and potent MAGL inhibitor (monoacylglycerol lipase inhibitor) . JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome. JZL184 attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action. JZL184 also suppresses inflammatory pain in the mouse carrageenan model.
Product Specifications
CAS Number
1101854-58-3
Product Name Alternative
JZL184 | JZL 184 | JZL-184
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 35 mg/mL; 67.24 mM
Smiles
OC (C1CCN (CC1) C (=O) Oc1ccc (cc1) [N+] (=O) [O-]) (c1ccc2OCOc2c1) c1ccc2OCOc2c1
Molecular Formula
C27H24N2O9
Molecular Weight
520.49
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-nitrophenyl 4- (bis (benzo[d][1,3]dioxol-5-yl) (hydroxy) methyl) piperidine-1-carboxylate.
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