Dolasetron
Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
Product Specifications
CAS Number
115956-12-2
Product Name Alternative
HSDB 7565 | HSDB7565 | Dolasetron | Dolasetronum
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 300 mg/mL; 924.87 mM
Smiles
[H][C@]12C[C@@H] (C[C@@H]3C[C@H] (C1) C (=O) CN23) OC (=O) c1c[nH]c2ccccc12
Molecular Formula
C19H20N2O3
Molecular Weight
324.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(6R) -3-oxooctahydro-1H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate
Available Sizes
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