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Linrodostat

BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor. (In Vitro) :Linrodostat (0.01-100 μM; 72 hours; SKOV-3 and Jurkat clone E6-1 cells) treatment reduces the number of viable cells compared with the non-treated control. Linrodostat also induces cell death at much lower concentrations and its IC50 is 6.3 μM.

Product Specifications

CAS Number

1923833-60-6

Product Name Alternative

BMS-986205 | ONO-7701

Purity

>98% (HPLC)

Solubility

DMSO : 50 mg/mL 121.68 mM; H2O : < 0.1 mg/mL

Smiles

Clc1ccc (cc1) NC (=O) [C@H] (C) [C@@H]2CC[C@@H] (CC2) c3ccnc4ccc (F) cc34

Molecular Formula

C24H24ClFN2O

Molecular Weight

410.91

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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