MMAD

MMAD, also known as Monomethyl auristatin D, is a highly potent tubulin inhibitor. MMAD is one of the auristatins, which are used as antibody drug conjugates (ADCs) .

Product Specifications

CAS Number

203849-91-6

Product Name Alternative

MMAD, Demethyldolastatin 10 | Monomethyl Dolastatin 10

Purity

>98% (HPLC)

Solubility

DMSO : 24.5 mg/mL 31.77 mM

Smiles

O=C (N[C@@H] (Cc1ccccc1) c2nccs2) [C@H] (C) [C@@H] (OC) [C@@H]3CCCN3C (=O) C[C@@H] (OC) [C@H] ([C@@H] (C) CC) N (C) C (=O) [C@@H] (NC (=O) [C@@H] (NC) C (C) C) C (C) C

Molecular Formula

C41H66N6O6S

Molecular Weight

771.06

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(S) -N- ((3R,4S,5S) -3-methoxy-1- ((S) -2- ((1R,2R) -1-methoxy-2-methyl-3-oxo-3- (((S) -2-phenyl-1- (thiazol-2-yl) ethyl) amino) propyl) pyrrolidin-1-yl) -5-methyl-1-oxoheptan-4-yl) -N,3-dimethyl-2- ((S) -3-methyl-2- (methylamino) butanamido) butanamide