Z-IETD-FMK
MDK4982, also known as Z-IETD-FMK, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B., The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. MDK4982 effectively inhibits influenza virus-induced apoptosis in HeLa cells. MDK4982 also inhibits granzyme B. MDK4982 has CAS#210344-98-2.
Product Specifications
CAS Number
210344-98-2
Product Name Alternative
Z-IE (OMe) TD (OMe) -FMK | Granzyme B Inhibitor III | Z-IETD-FMK
Purity
>98% (HPLC)
Solubility
DMSO : 125 mg/mL 190.93 mM; H2O : < 0.1 mg/mL
Smiles
CC[C@H] (C) [C@@H] (C (=O) N[C@@H] (CCC (=O) OC) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (=O) OC) C (=O) CF) NC (=O) OCC1=CC=CC=C1
Molecular Formula
C30H43FN4O11
Molecular Weight
654.68
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(5S,8S,11S,14S) -5- ((S) -sec-butyl) -8- (2-carboxyethyl) -14- (2-fluoroacetyl) -11- ((R) -1-hydroxyethyl) -3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oic acid
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