What is the catalog number for Tretazicar?

The catalog number for Tretazicar is orb1222509.

What sizes are available for Tretazicar?

Tretazicar is available in the following size(s): 100 mg, 200 mg, 500 mg, 1 g, 5 mg, 10 mg, 25 mg, 50 mg.

How many pack sizes does Tretazicar come in?

Tretazicar is available in 8 different pack sizes.

Is Tretazicar in stock?

Tretazicar is currently made to order / not held in immediate stock. Contact us for lead time.

Tretazicar

Tretazicar (CB1954) is a dinitrobenzamide prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. CB1954 has been proposed for use in enzyme-prodrug gene therapy systems with the Escherichia coli enzyme nitroreductase (Ntr) . Ntr converts CB1954 to 2- and 4-hydroxylamino derivatives, whereupon the non-enzymatic reaction of the 4-hydroxylamino derivative with cellular thio- esters generates a potent cytotoxic bifunctional alkylating agent capable of cross-linking DNA.