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Polygalacic acid

Polygalacic acid (PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and elevates levels of acetylcholine (ACh) in the hippocampus and frontal cortex, PA also significantly ameliorates neuroinflammation and oxidative stress in mice; suggest that PA might exert a significant neuroprotective effect on cognitive impairment, driven in part by the modulation of cholinergic activity and neuroinflammation. Polygalacic acid shows significant postingestive effects on Spodoptera littoralis larvae.

Product Specifications

CAS Number

22338-71-2

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 50 mg/mL (99.07 mM)

Smiles

O=C (O) [C@]53CCC (C) (C) C[C@H]5C4=CC[C@H]2[C@@] (C) (CC[C@@H]1[C@]2 (C) C[C@H] (O) [C@H] (O) [C@@]1 (C) CO) [C@]4 (C) C[C@H]3O

Molecular Formula

C30H48O6

Molecular Weight

504.7

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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