Phellopterin
Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.
Product Specifications
CAS Number
2543-94-4
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (332.99 mM)
Smiles
COc1c2ccoc2c (OCC=C (C) C) c2oc (=O) ccc12
Molecular Formula
C17H16O5
Molecular Weight
300.31
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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