Alpha-Hederin

Alpha-Hederin is Derived from beta-amyrin; other hederigenin based saponins are available. It induces apoptosis in hepatocellular carcinoma cells. (In Vitro) :alpha-Hederin (α-Hederin) is cytotoxic and inhibits proliferation in both cel lines at rather low concentrations. alpha-Hederin (α-Hederin) reduces the mitotic activity in treated cells. (In Vivo) :alpha-Hederin (α-Hederin) has preventive effect on sensitized rats like thymoquinone. It may intervene in miRNA-126 expression, which consequently could interfere with IL-13 secretion pathway leading to a reduction in inflammatory responses.

Product Specifications

CAS Number

27013-91-8

Product Name Alternative

Alpha-Hederin

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL 133.16 mM; H2O : < 0.1 mg/mL

Smiles

C[C@H]1[C@@H] ([C@H] ([C@H] ([C@@H] (O1) O[C@@H]1[C@H] ([C@H] (CO[C@H]1O[C@H]1CC[C@]2 ([C@H] ([C@]1 (C) CO) CC[C@@]1 ([C@@H]2CC=C2[C@]1 (CC[C@@]1 ([C@H]2CC (CC1) (C) C) C (=O) O) C) C) C) O) O) O) O) O