SRT3109
SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.
Product Specifications
CAS Number
1204707-71-0
Product Name Alternative
SRT3109 | SRT-3109
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL; 210.29 mM
Smiles
C[C@H] ([C@H] (CO) O) Nc1cc (nc (n1) SCc1c (c (ccc1) F) F) NS (=O) (=O) N1CCC1
Molecular Formula
C18H23F2N5O4S2
Molecular Weight
475.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2- ((2,3-difluorobenzyl) thio) -6- (((2R,3R) -3,4-dihydroxybutan-2-yl) amino) pyrimidin-4-yl) azetidine-1-sulfonamide
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