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SRT3109

SRT3109 is a CXCR2 ligand. CXCR2 ligands are potent chemoattractants for neutrophils and play a key role in the emigration of neutrophils from the blood to sites of tissue inflammation. Moreover, CXCR2 signaling may also regulate neutrophil mobilization from the bone marrow. Deletion of the chemokine receptor CXCR2 prevents the recruitment of neutrophils into tissues and subsequent development of experimental Lyme arthritis.

Product Specifications

CAS Number

1204707-71-0

Product Name Alternative

SRT3109 | SRT-3109

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 100 mg/mL; 210.29 mM

Smiles

C[C@H] ([C@H] (CO) O) Nc1cc (nc (n1) SCc1c (c (ccc1) F) F) NS (=O) (=O) N1CCC1

Molecular Formula

C18H23F2N5O4S2

Molecular Weight

475.53

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (2- ((2,3-difluorobenzyl) thio) -6- (((2R,3R) -3,4-dihydroxybutan-2-yl) amino) pyrimidin-4-yl) azetidine-1-sulfonamide

Available Sizes

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