LM10
LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively) . LM10 exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. LM10 reduces growth of TDO-expressing P815 mastocytoma tumors in mice.
Product Specifications
CAS Number
1316695-35-8
Product Name Alternative
LM10 | LM 10 | LM-10
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (218.14 mM)
Smiles
Fc2cc3ncc (/C=C/c1nnnn1) c3cc2
Molecular Formula
C11H8FN5
Molecular Weight
229.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6-fluoro-3-[ (E) -2- (1H-1,2,3,4-tetrazol-5-yl) ethenyl]-1H-indole
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