BMS-5
LIMKI-3, also known as BMS-3, is a Potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively) . Inhibits cofilin phosphorylation in MDA-MB-231 breast cancer cells. Reduces MDA-MB-231 tumor cell invasion in a 3D matrigel invasion assay.
Product Specifications
CAS Number
1338247-35-0
Product Name Alternative
LIMKI-3 | LIMKI 3 | LIMKI3 | BMS-5
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 34 mg/mL; 78.83 mM
Smiles
O=C (Nc1ncc (s1) c2cc (nn2c3c (Cl) cccc3Cl) C (F) F) C (C) C
Molecular Formula
C17H14Cl2F2N4OS
Molecular Weight
431.29
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N-[5-[1- (2,6-Dichlorophenyl) -3- (difluoromethyl) -1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide
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