Koumine
Koumine is an indole alkaloid. It reverses thermal hyperalgesia and mechanical allodynia induced by sciatic nerve chronic constriction injury (CCI) in rats in a dose-dependent manner. This effect is mediated by elevated allopregnanolone levels in the spinal cord.
Product Specifications
CAS Number
1358-76-5
Product Name Alternative
Koumine
Purity
>98% (HPLC)
Solubility
DMSO : 31.25 mg/mL 101.99 mM
Smiles
CN1CC2 (C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4) C=C
Molecular Formula
C20H22N2O
Molecular Weight
306.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(4aR,6R,11cS) -2-methyl-11c-vinyl-1,2,3,4,4a,5,6,11c-octahydro-6,4- (epoxymethano) -3,11b-methanopyrido[4,3-c]carbazole
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