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RG 14620

RG-14620 is an EGFR inhibitor. It is a non-phenolic tyrphostin analog, which is selective for the EGF receptor and long acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=3 μM) as well as tumor growth in vivo.

Product Specifications

CAS Number

136831-49-7

Product Name Alternative

RG 14620 | TYRPHOSTIN RG 14620.

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 26 mg/mL; 94.50 mM

Smiles

C1cc (cnc1) /C (=C\c1cc (cc (c1) Cl) Cl) /C#N

Molecular Formula

C14H8Cl2N2

Molecular Weight

275.13

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(E) -3- (3,5-dichlorophenyl) -2- (pyridin-3-yl) acrylonitrile

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