ML297
ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively) . ML297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters.
Product Specifications
CAS Number
1443246-62-5
Product Name Alternative
ML297 | ML 297 | ML-297
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (761.45 mM)
Smiles
Fc1ccc (cc1F) NC (=O) Nc3cc (C) nn3c2ccccc2
Molecular Formula
C17H14F2N4O
Molecular Weight
328.11
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1- (3,4-difluorophenyl) -3- (5-methyl-2-phenylpyrazol-3-yl) urea
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