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CCG-203971

CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM), as determined by a scratch wound assay. CCG-203971 causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.

Product Specifications

CAS Number

1443437-74-8

Product Name Alternative

CCG-203971 | CCG 203971

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 155 mg/mL 379.08 mM; H2O : < 0.1 mg/mL

Smiles

O=C (C1CN (C (C2=CC=CC (C3=CC=CO3) =C2) =O) CCC1) NC4=CC=C (Cl) C=C4

Molecular Formula

C23H21ClN2O3

Molecular Weight

408.88

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (4-chlorophenyl) -1-[3- (furan-2-yl) benzoyl]piperidine-3-carboxamide

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