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CW069

CW069 is an allosteric inhibitor of HSET. CW069 showed marked activity against HSET in vitro. The inhibitor induced multipolar mitoses only in cells containing supernumerary centrosomes. CW069 therefore constitutes a valuable tool for probing HSET function and, by reducing the growth of cells containing supernumerary centrosomes, paves the way for new cancer therapeutics.

Product Specifications

CAS Number

1594094-64-0

Product Name Alternative

CW069 | CW-069 | CW 069

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 52 mg/mL; 103.93 mM

Smiles

O=C (O) c1cc (I) ccc1NC (=O) [C@@H] (NCc1ccccc1) Cc1ccccc1

Molecular Formula

C23H21IN2O3

Molecular Weight

500.33

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

5-Iodo-2-[[ (2S) -1-oxo-3-phenyl-2-[ (phenylmethyl) amino]propyl]amino]-benzoic acid

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