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BML-190

BML-190, also known as IMMA and LM-4131 or Indomethacin Morpholinylamide, is selective CB2 receptor agonist. The binding constant for the CB2 receptor is 435 nM compared to >20,000 nM for the cannabinoid receptor, CB1. BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB (2) receptor and 16z44. BML-190 acts as inverse agonist at the human CB (2) receptor acting via G alpha (i/o) and G alpha (q) family-coupled pathways.

Product Specifications

CAS Number

2854-32-2

Product Name Alternative

BML-190 | BML 190 | BML190 | Indomethacin Morpholinylamide.

Purity

>98% (HPLC)

Solubility

DMSO : 50 mg/mL 117.13 mM

Smiles

Cc1c (c2c (n1C (=O) c1ccc (cc1) Cl) ccc (c2) OC) CC (=O) N1CCOCC1

Molecular Formula

C23H23ClN2O4

Molecular Weight

426.89

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-[1- (4-chlorobenzoyl) -5-methoxy-2-methyl-1H-indol-3-yl]-1- (4-morpholinyl) -ethanone

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