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TRAM-34

TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM) . Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli, and does not block cytochrome P450.

Product Specifications

CAS Number

289905-88-0

Product Name Alternative

TRAM-34 | TRAM34 | TRAM 34

Purity

>98% (HPLC)

Solubility

DMSO : ≥ 3.5 mg/mL; 10.15 mM

Smiles

N1 (nccc1) C (c1ccccc1) (c1ccccc1) c1c (cccc1) Cl

Molecular Formula

C22H17ClN2

Molecular Weight

344.84

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1-[ (2-Chlorophenyl) diphenylmethyl]-1H-pyrazole

Available Sizes

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